Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0004200 | Exon-Exon | chr1:243708812-243801044 | chr1:243545510-243637742 | 822 nt | 0.4027 |
| hsa_AKT3_0004300 | Exon-Exon | chr1:243708812-244006584 | chr1:243545510-243843282 | 1363 nt | 0.4109 |
| hsa_AKT3_0007000 | Exon-Exon | chr1:243716031-243736350 | chr1:243552729-243573048 | 467 nt | 0.4283 |
| hsa_AKT3_0007100 | Exon-Exon | chr1:243716031-243778463 | chr1:243552729-243615161 | 602 nt | 0.4203 |
| hsa_AKT3_0007200 | Exon-Exon | chr1:243716031-243801044 | chr1:243552729-243637742 | 734 nt | 0.4046 |
| hsa_chr1_0715200 | Intergenic-Intergenic | chr1:243723200-243723386 | chr1:243559898-243560084 | 187 nt | 0.4332 |
| hsa_AKT3_0008600 | Exon-Exon | chr1:243727022-243736350 | chr1:243563720-243573048 | 252 nt | 0.4524 |
| hsa_AKT3_0008700 | Exon-Exon | chr1:243727022-243778463 | chr1:243563720-243615161 | 387 nt | 0.4315 |
| hsa_AKT3_0008800 | Exon-Exon | chr1:243727022-243801044 | chr1:243563720-243637742 | 519 nt | 0.4066 |
| hsa_AKT3_0008900 | Exon-Exon | chr1:243727022-243809339 | chr1:243563720-243646037 | 664 nt | 0.4111 |
Showing 11 to 20 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].