Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0016800 Exon-Exon chr1:243809195-243809339 chr1:243645893-243646037 145 nt 0.4276
hsa_AKT3_0016900 Exon-Exon chr1:243809195-243828185 chr1:243645893-243664883 112 nt 0.3750
hsa_AKT3_0017000 Intron-Exon-Intron chr1:243809195-243846612 chr1:243645893-243683310 114 nt 0.3684
hsa_AKT3_0017100 Intron-Exon-Intron chr1:243809195-243863517 chr1:243645893-243700215 156 nt 0.3846
hsa_AKT3_0016700 Intron-Exon-Intron chr1:243809195-243898392 chr1:243645893-243735090 250 nt 0.3640
hsa_AKT3_0017200 Intron-Exon-Intron chr1:243809195-243905345 chr1:243645893-243742043 231 nt 0.4069
hsa_chr1_0715800 Intergenic-Intergenic chr1:243809220-243858940 chr1:243645918-243695638 280 nt 0.4107
hsa_AKT3_0017300 Intron-Exon-Intron chr1:243823377-244006584 chr1:243660075-243843282 831 nt 0.4128
hsa_AKT3_0018000 Intron-Exon-Intron chr1:243828074-243846612 chr1:243664772-243683310 226 nt 0.3717
hsa_AKT3_0018100 Intron-Exon-Intron chr1:243828074-243847246 chr1:243664772-243683944 112 nt 0.3750
Showing 191 to 200 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].