Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0018200 | Intron-Exon-Intron | chr1:243828074-243890495 | chr1:243664772-243727193 | 118 nt | 0.3814 |
| hsa_AKT3_0017600 | Intron-Exon-Intron | chr1:243828074-243898392 | chr1:243664772-243735090 | 250 nt | 0.3600 |
| hsa_AKT3_0017700 | Intron-Exon-Intron | chr1:243828074-243898402 | chr1:243664772-243735100 | 250 nt | 0.3640 |
| hsa_AKT3_0018300 | Intron-Exon-Intron | chr1:243828074-243899049 | chr1:243664772-243735747 | 118 nt | 0.3729 |
| hsa_AKT3_0018400 | Intron-Exon-Intron | chr1:243828074-243905345 | chr1:243664772-243742043 | 92 nt | 0.3804 |
| hsa_AKT3_0017800 | Intron-Exon-Intron | chr1:243828074-243981737 | chr1:243664772-243818435 | 250 nt | 0.3240 |
| hsa_AKT3_0017900 | Exon-Exon | chr1:243828074-244006447 | chr1:243664772-243843145 | 259 nt | 0.3861 |
| hsa_AKT3_0018500 | Exon-Exon | chr1:243828074-244006584 | chr1:243664772-243843282 | 510 nt | 0.4098 |
| hsa_AKT3_0018600 | Intron-Intron | chr1:243834121-243846612 | chr1:243670819-243683310 | 250 nt | 0.3080 |
| hsa_chr1_0715900 | Intergenic-Intergenic | chr1:243835358-243835499 | chr1:243672056-243672197 | 142 nt | 0.4859 |
Showing 201 to 210 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].