Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0018700 Intron-Exon-Intron chr1:243841171-244006584 chr1:243677869-243843282 158 nt 0.4937
hsa_AKT3_0018800 Intron-Exon-Intron chr1:243844304-244006584 chr1:243681002-243843282 398 nt 0.4196
hsa_AKT3_0019400 Intron-Exon-Intron chr1:243846499-243863520 chr1:243683197-243700218 114 nt 0.3684
hsa_AKT3_0019000 Intron-Exon-Intron chr1:243846499-243873112 chr1:243683197-243709810 250 nt 0.2440
hsa_AKT3_0019100 Intron-Exon-Intron chr1:243846499-243873171 chr1:243683197-243709869 250 nt 0.2880
hsa_AKT3_0019500 Intron-Exon-Intron chr1:243846499-243873175 chr1:243683197-243709873 123 nt 0.3496
hsa_AKT3_0019600 Intron-Exon-Intron chr1:243846499-243874118 chr1:243683197-243710816 233 nt 0.3691
hsa_AKT3_0019700 Intron-Exon-Intron chr1:243846499-243898402 chr1:243683197-243735100 120 nt 0.3667
hsa_AKT3_0019200 Intron-Exon-Intron chr1:243846499-243898418 chr1:243683197-243735116 250 nt 0.3280
hsa_AKT3_0019800 Intron-Exon-Intron chr1:243846499-243899049 chr1:243683197-243735747 120 nt 0.3667
Showing 211 to 220 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].