Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0019900 | Intron-Exon-Intron | chr1:243846499-243905345 | chr1:243683197-243742043 | 417 nt | 0.3813 |
| hsa_AKT3_0019300 | Intron-Exon-Intron | chr1:243846499-243953111 | chr1:243683197-243789809 | 250 nt | 0.2880 |
| hsa_AKT3_0020000 | Intron-Exon-Intron | chr1:243846499-244006584 | chr1:243683197-243843282 | 398 nt | 0.4196 |
| hsa_AKT3_0020100 | Intron-Exon-Intron | chr1:243850216-244006584 | chr1:243686914-243843282 | 250 nt | 0.3960 |
| hsa_chr1_0716100 | Intergenic-Intergenic | chr1:243852888-243853110 | chr1:243689586-243689808 | 223 nt | 0.4215 |
| hsa_AKT3_0020200 | Intron-Exon-Intron | chr1:243855479-243890495 | chr1:243692177-243727193 | 64 nt | 0.4219 |
| hsa_chr1_0716200 | Intergenic-Intergenic | chr1:243856982-243857330 | chr1:243693680-243694028 | 349 nt | 0.3381 |
| hsa_AKT3_0020700 | Intron-Exon-Intron | chr1:243858893-243891066 | chr1:243695591-243727764 | 250 nt | 0.2960 |
| hsa_AKT3_0020800 | Intron-Exon-Intron | chr1:243858893-243898402 | chr1:243695591-243735100 | 126 nt | 0.3730 |
| hsa_AKT3_0020900 | Intron-Exon-Intron | chr1:243858893-243898418 | chr1:243695591-243735116 | 126 nt | 0.3730 |
Showing 221 to 230 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].