Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0021000 | Intron-Exon-Intron | chr1:243858893-243904152 | chr1:243695591-243740850 | 426 nt | 0.4272 |
| hsa_AKT3_0021100 | Intron-Exon-Intron | chr1:243858893-243952128 | chr1:243695591-243788826 | 126 nt | 0.3730 |
| hsa_AKT3_0021200 | Intron-Exon-Intron | chr1:243858893-243991910 | chr1:243695591-243828608 | 141 nt | 0.4043 |
| hsa_chr1_0716300 | Intergenic-Intergenic | chr1:243858923-244006458 | chr1:243695621-243843156 | 128 nt | 0.3828 |
| hsa_chr1_0716400 | Intergenic-Intergenic | chr1:243859270-243859804 | chr1:243695968-243696502 | 535 nt | 0.2953 |
| hsa_AKT3_0021300 | Intron-Intron | chr1:243863474-243898402 | chr1:243700172-243735100 | 400 nt | 0.4125 |
| hsa_AKT3_0021400 | Intron-Intron | chr1:243863969-243866948 | chr1:243700667-243703646 | 2980 nt | 0.3336 |
| hsa_AKT3_0021500 | Intron-Intron | chr1:243865530-243865713 | chr1:243702228-243702411 | 184 nt | 0.3859 |
| hsa_AKT3_0021600 | Intron-Intron | chr1:243866202-243905345 | chr1:243702900-243742043 | 1568 nt | 0.3227 |
| hsa_chr1_0716500 | Intergenic-Intergenic | chr1:243874195-243874559 | chr1:243710893-243711257 | 365 nt | 0.4575 |
Showing 231 to 240 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].