Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr1_0716600 | Intergenic-Intergenic | chr1:243875256-243875535 | chr1:243711954-243712233 | 280 nt | 0.3607 |
| hsa_chr1_0716700 | Intergenic-Intergenic | chr1:243876023-243878588 | chr1:243712721-243715286 | 2566 nt | 0.3468 |
| hsa_chr1_0716800 | Intergenic-Intergenic | chr1:243882380-243882871 | chr1:243719078-243719569 | 492 nt | 0.3557 |
| hsa_chr1_0716900 | Intergenic-Intergenic | chr1:243888274-243888663 | chr1:243724972-243725361 | 390 nt | 0.4282 |
| hsa_AKT3_0021700 | Intron-Exon-Intron | chr1:243890425-244006584 | chr1:243727123-243843282 | 250 nt | 0.3680 |
| hsa_AKT3_0021800 | Intron-Intron | chr1:243890429-243905345 | chr1:243727127-243742043 | 221 nt | 0.3710 |
| hsa_AKT3_0021900 | Intron-Exon-Intron | chr1:243890429-244006584 | chr1:243727127-243843282 | 311 nt | 0.4469 |
| hsa_AKT3_0022100 | Intron-Intron | chr1:243898210-243905345 | chr1:243734908-243742043 | 1207 nt | 0.3513 |
| hsa_AKT3_0022000 | Intron-Intron | chr1:243898210-243911815 | chr1:243734908-243748513 | 250 nt | 0.2880 |
| hsa_AKT3_0022300 | Intron-Intron | chr1:243898242-243905345 | chr1:243734940-243742043 | 1175 nt | 0.3557 |
Showing 241 to 250 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].