Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0022200 | Intron-Exon-Intron | chr1:243898242-244006584 | chr1:243734940-243843282 | 250 nt | 0.3960 |
| hsa_AKT3_0022400 | Intron-Intron | chr1:243898260-243905345 | chr1:243734958-243742043 | 615 nt | 0.4260 |
| hsa_AKT3_0022500 | Intron-Intron | chr1:243898260-243911815 | chr1:243734958-243748513 | 238 nt | 0.4412 |
| hsa_AKT3_0022600 | Intron-Exon-Intron | chr1:243898260-244006584 | chr1:243734958-243843282 | 632 nt | 0.4478 |
| hsa_AKT3_0022700 | Intron-Intron | chr1:243898262-243911815 | chr1:243734960-243748513 | 250 nt | 0.3400 |
| hsa_AKT3_0022800 | Intron-Intron | chr1:243898909-243905345 | chr1:243735607-243742043 | 147 nt | 0.3946 |
| hsa_chr1_0717000 | Intergenic-Intergenic | chr1:243900420-243900581 | chr1:243737118-243737279 | 162 nt | 0.4198 |
| hsa_AKT3_0023000 | Intron-Intron | chr1:243902825-243905345 | chr1:243739523-243742043 | 86 nt | 0.3721 |
| hsa_AKT3_0022900 | Intron-Intron | chr1:243902825-243910889 | chr1:243739523-243747587 | 250 nt | 0.3280 |
| hsa_AKT3_0023100 | Intron-Intron | chr1:243902825-243952128 | chr1:243739523-243788826 | 256 nt | 0.4375 |
Showing 251 to 260 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].