Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0023200 | Intron-Exon-Intron | chr1:243902825-244006584 | chr1:243739523-243843282 | 375 nt | 0.4400 |
| hsa_AKT3_0023300 | Intron-Intron | chr1:243904015-243904316 | chr1:243740713-243741014 | 302 nt | 0.3940 |
| hsa_AKT3_0023400 | Intron-Intron | chr1:243904015-243905345 | chr1:243740713-243742043 | 1331 nt | 0.3216 |
| hsa_chr1_0717100 | Intergenic-Intergenic | chr1:243909328-243909554 | chr1:243746026-243746252 | 227 nt | 0.3040 |
| hsa_chr1_0717200 | Intergenic-Intergenic | chr1:243917788-243917991 | chr1:243754486-243754689 | 204 nt | 0.5784 |
| hsa_chr1_0717300 | Intergenic-Intergenic | chr1:243920645-243921300 | chr1:243757343-243757998 | 656 nt | 0.4543 |
| hsa_chr1_0717400 | Intergenic-Intergenic | chr1:243928898-243930151 | chr1:243765596-243766849 | 1254 nt | 0.3461 |
| hsa_AKT3_0023600 | Intron-Intron | chr1:243941188-243941399 | chr1:243777886-243778097 | 212 nt | 0.4245 |
| hsa_AKT3_0023700 | Intron-Intron | chr1:243941188-243942159 | chr1:243777886-243778857 | 972 nt | 0.3601 |
| hsa_AKT3_0023800 | Intron-Intron | chr1:243943743-243949063 | chr1:243780441-243785761 | 250 nt | 0.3240 |
Showing 261 to 270 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].