Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0023900 | Intron-Intron | chr1:243944251-243944617 | chr1:243780949-243781315 | 367 nt | 0.2725 |
| hsa_AKT3_0024000 | Intron-Intron | chr1:243945418-243952419 | chr1:243782116-243789117 | 250 nt | 0.3680 |
| hsa_chr1_0717500 | Intergenic-Intergenic | chr1:243947539-243947681 | chr1:243784237-243784379 | 143 nt | 0.4476 |
| hsa_chr1_0717600 | Intergenic-Intergenic | chr1:243947549-243948246 | chr1:243784247-243784944 | 698 nt | 0.4756 |
| hsa_AKT3_0024100 | Intron-Intron | chr1:243950083-243952128 | chr1:243786781-243788826 | 2046 nt | 0.3759 |
| hsa_AKT3_0024200 | Intron-Intron | chr1:243951434-243952128 | chr1:243788132-243788826 | 220 nt | 0.4227 |
| hsa_AKT3_0024300 | Intron-Intron | chr1:243952004-243954401 | chr1:243788702-243791099 | 2398 nt | 0.4041 |
| hsa_chr1_0717700 | Intergenic-Intergenic | chr1:243954135-243954526 | chr1:243790833-243791224 | 392 nt | 0.3648 |
| hsa_chr1_0717800 | Intergenic-Intergenic | chr1:243959051-243963790 | chr1:243795749-243800488 | 250 nt | 0.4080 |
| hsa_chr1_0717900 | Intergenic-Intergenic | chr1:243959132-243959384 | chr1:243795830-243796082 | 253 nt | 0.4783 |
Showing 271 to 280 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].