Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0024400 | Intron-Intron | chr1:243960454-243960697 | chr1:243797152-243797395 | 244 nt | 0.3566 |
| hsa_AKT3_0024500 | Intron-Intron | chr1:243960457-243960697 | chr1:243797155-243797395 | 241 nt | 0.3568 |
| hsa_chr1_0718000 | Intergenic-Intergenic | chr1:243961487-243963790 | chr1:243798185-243800488 | 2304 nt | 0.3837 |
| hsa_chr1_0718100 | Intergenic-Intergenic | chr1:243961506-243963745 | chr1:243798204-243800443 | 2240 nt | 0.3772 |
| hsa_AKT3_0024600 | Intron-Intron | chr1:243964088-243978965 | chr1:243800786-243815663 | 250 nt | 0.2440 |
| hsa_AKT3_0024700 | Intron-Intron | chr1:243977294-243979043 | chr1:243813992-243815741 | 1750 nt | 0.3566 |
| hsa_AKT3_0024800 | Intron-Intron | chr1:243977670-243977951 | chr1:243814368-243814649 | 282 nt | 0.3050 |
| hsa_chr1_0718200 | Intergenic-Intergenic | chr1:243979262-243980476 | chr1:243815960-243817174 | 1215 nt | 0.3695 |
| hsa_chr1_0718300 | Intergenic-Intergenic | chr1:243980141-243980523 | chr1:243816839-243817221 | 383 nt | 0.4386 |
| hsa_AKT3_0024900 | Intron-Intron | chr1:243980153-243981737 | chr1:243816851-243818435 | 1585 nt | 0.3956 |
Showing 281 to 290 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].