Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0009000 | Exon-Exon | chr1:243727022-243859018 | chr1:243563720-243695716 | 902 nt | 0.4013 |
| hsa_AKT3_0009100 | Exon-Exon | chr1:243727022-244006584 | chr1:243563720-243843282 | 1060 nt | 0.4151 |
| hsa_AKT3_0010200 | Exon-Exon | chr1:243736228-243777041 | chr1:243572926-243613739 | 192 nt | 0.4479 |
| hsa_AKT3_0010300 | Exon-Exon | chr1:243736228-243778463 | chr1:243572926-243615161 | 258 nt | 0.4302 |
| hsa_AKT3_0010400 | Exon-Exon | chr1:243736228-243801044 | chr1:243572926-243637742 | 390 nt | 0.3974 |
| hsa_AKT3_0010500 | Exon-Exon | chr1:243736228-243828185 | chr1:243572926-243664883 | 647 nt | 0.4003 |
| hsa_AKT3_0010600 | Exon-Exon | chr1:243736228-243859018 | chr1:243572926-243695716 | 773 nt | 0.3959 |
| hsa_AKT3_0010700 | Exon-Exon | chr1:243736228-244006584 | chr1:243572926-243843282 | 931 nt | 0.4125 |
| hsa_chr1_0715700 | Intergenic-Intergenic | chr1:243772332-243772728 | chr1:243609030-243609426 | 397 nt | 0.3426 |
| hsa_AKT3_0012200 | Exon-Exon | chr1:243776973-243778463 | chr1:243613671-243615161 | 135 nt | 0.3926 |
Showing 21 to 30 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].