Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0025000 | Intron-Intron | chr1:243983515-243989173 | chr1:243820213-243825871 | 250 nt | 0.3200 |
| hsa_AKT3_0025100 | Intron-Intron | chr1:243988654-243989173 | chr1:243825352-243825871 | 520 nt | 0.3423 |
| hsa_AKT3_0025200 | Intron-Intron | chr1:243988673-243989394 | chr1:243825371-243826092 | 722 nt | 0.3947 |
| hsa_AKT3_0025300 | Intron-Intron | chr1:243989466-243989690 | chr1:243826164-243826388 | 225 nt | 0.3778 |
| hsa_AKT3_0025400 | Intron-Exon-Intron | chr1:243991789-244006584 | chr1:243828487-243843282 | 280 nt | 0.4821 |
| hsa_AKT3_0025500 | Intron-Intron | chr1:243994134-243994359 | chr1:243830832-243831057 | 226 nt | 0.4027 |
| hsa_AKT3_0025600 | Intron-Intron | chr1:243994134-243994387 | chr1:243830832-243831085 | 254 nt | 0.4173 |
| hsa_chr1_0718400 | Intergenic-Intergenic | chr1:243996490-243996676 | chr1:243833188-243833374 | 187 nt | 0.4225 |
| hsa_AKT3_0025700 | Intron-Intron | chr1:243998579-243998829 | chr1:243835277-243835527 | 251 nt | 0.3546 |
| hsa_AKT3_0025800 | Intron-Exon-Intron | chr1:244002624-244006584 | chr1:243839322-243843282 | 250 nt | 0.3600 |
Showing 291 to 300 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].