Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr1_0718500 | Intergenic-Intergenic | chr1:244005087-244005840 | chr1:243841785-243842538 | 754 nt | 0.3249 |
| hsa_chr1_0718600 | Intergenic-Intergenic | chr1:244005620-244005773 | chr1:243842318-243842471 | 154 nt | 0.4026 |
| hsa_AKT3_0026000 | Intron-Exon-Intron | chr1:244006427-244007318 | chr1:243843125-243844016 | 33 nt | 0.3636 |
| hsa_RP11-269F20.1_0000100 | Intergenic-Exon-Intergenic | chr1:243668547-243736259 | chr1:243505245-243572957 | 657 nt | 0.4064 |
| hsa_RP11-370K11.1_0000100 | Intron-Intron | chr1:243873053-243898402 | chr1:243709751-243735100 | 250 nt | 0.3480 |
| hsa_RP11-370K11.1_0000200 | Intron-Intron | chr1:243884302-243884460 | chr1:243721000-243721158 | 159 nt | 0.4528 |
| hsa_RP11-370K11.1_0000300 | Intron-Intron | chr1:243887889-243890495 | chr1:243724587-243727193 | 2607 nt | 0.3702 |
| hsa_RP11-370K11.1_0000400 | Intron-Intron | chr1:243890429-243891066 | chr1:243727127-243727764 | 67 nt | 0.4328 |
| hsa_RP11-370K11.1_0000500 | Intron-Exon-Intron | chr1:243890429-243902915 | chr1:243727127-243739613 | 67 nt | 0.4328 |
| hsa_RP11-370K11.1_0000600 | Intron-Intron | chr1:243893222-243893476 | chr1:243729920-243730174 | 255 nt | 0.4706 |
Showing 301 to 310 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].