Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0012300 | Exon-Exon | chr1:243776973-243801044 | chr1:243613671-243637742 | 267 nt | 0.3633 |
| hsa_AKT3_0012400 | Exon-Exon | chr1:243776973-243809339 | chr1:243613671-243646037 | 412 nt | 0.3859 |
| hsa_AKT3_0012500 | Exon-Exon | chr1:243776973-243828185 | chr1:243613671-243664883 | 524 nt | 0.3836 |
| hsa_AKT3_0012600 | Exon-Exon | chr1:243776973-243859018 | chr1:243613671-243695716 | 650 nt | 0.3815 |
| hsa_AKT3_0012700 | Exon-Exon | chr1:243776973-244006584 | chr1:243613671-243843282 | 808 nt | 0.4035 |
| hsa_AKT3_0014200 | Exon-Exon | chr1:243778398-243859018 | chr1:243615096-243695716 | 581 nt | 0.3787 |
| hsa_AKT3_0015000 | Intron-Intron | chr1:243788211-243791306 | chr1:243624909-243628004 | 250 nt | 0.3360 |
| hsa_AKT3_0015100 | Exon-Exon | chr1:243800913-243809233 | chr1:243637611-243645931 | 171 nt | 0.3509 |
| hsa_AKT3_0015200 | Exon-Exon | chr1:243800913-243828185 | chr1:243637611-243664883 | 389 nt | 0.3805 |
| hsa_AKT3_0015300 | Exon-Exon | chr1:243800913-243859018 | chr1:243637611-243695716 | 515 nt | 0.3786 |
Showing 31 to 40 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].