Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0015400 | Exon-Exon | chr1:243800913-244006584 | chr1:243637611-243843282 | 673 nt | 0.4056 |
| hsa_AKT3_0016300 | Exon-Exon | chr1:243800982-243828177 | chr1:243637680-243664875 | 312 nt | 0.3814 |
| hsa_AKT3_0016500 | Exon-Exon | chr1:243809195-243859018 | chr1:243645893-243695716 | 383 nt | 0.3943 |
| hsa_AKT3_0016600 | Exon-Exon | chr1:243809195-244006584 | chr1:243645893-243843282 | 541 nt | 0.4233 |
| hsa_AKT3_0017400 | Exon-Exon | chr1:243828074-243859018 | chr1:243664772-243695716 | 238 nt | 0.3739 |
| hsa_AKT3_0017500 | Intron-Exon-Intron | chr1:243828074-243898418 | chr1:243664772-243735116 | 250 nt | 0.3400 |
| hsa_AKT3_0018900 | Intron-Exon-Intron | chr1:243846499-243859018 | chr1:243683197-243695716 | 250 nt | 0.2800 |
| hsa_chr1_0716000 | Intergenic-Intergenic | chr1:243852875-243853025 | chr1:243689573-243689723 | 151 nt | 0.4040 |
| hsa_AKT3_0020300 | Exon-Exon | chr1:243858893-243859018 | chr1:243695591-243695716 | 126 nt | 0.3730 |
| hsa_AKT3_0020400 | Intron-Exon-Intron | chr1:243858893-243899049 | chr1:243695591-243735747 | 250 nt | 0.3080 |
Showing 41 to 50 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].