Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0020500 | Intron-Exon-Intron | chr1:243858893-243905345 | chr1:243695591-243742043 | 250 nt | 0.2880 |
| hsa_AKT3_0020600 | Exon-Exon | chr1:243858893-244006584 | chr1:243695591-243843282 | 284 nt | 0.4401 |
| hsa_AKT3_0023500 | Intron-Intron | chr1:243927963-243928163 | chr1:243764661-243764861 | 201 nt | 0.3184 |
| hsa_AKT3_0025900 | Exon-Exon | chr1:244006427-244006584 | chr1:243843125-243843282 | 158 nt | 0.4937 |
| hsa_AKT3_0000700 | Exon-Intron | chr1:243663039-243668636 | chr1:243499737-243505334 | 50 nt | 0.3600 |
| hsa_AKT3_0000800 | Exon-Exon | chr1:243663039-243675728 | chr1:243499737-243512426 | 103 nt | 0.3301 |
| hsa_AKT3_0000200 | Exon-Exon | chr1:243663039-243708899 | chr1:243499737-243545597 | 241 nt | 0.3568 |
| hsa_AKT3_0000900 | Exon-Exon | chr1:243663039-243716058 | chr1:243499737-243552756 | 28 nt | 0.3929 |
| hsa_AKT3_0000300 | Exon-Exon | chr1:243663039-243716245 | chr1:243499737-243552943 | 456 nt | 0.3772 |
| hsa_AKT3_0000400 | Exon-Intron | chr1:243663039-243716392 | chr1:243499737-243553090 | 603 nt | 0.3466 |
Showing 51 to 60 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].