Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0001000 | Exon-Exon | chr1:243663039-243801010 | chr1:243499737-243637708 | 50 nt | 0.3600 |
| hsa_AKT3_0001100 | Exon-Intron | chr1:243663039-243846612 | chr1:243499737-243683310 | 114 nt | 0.3684 |
| hsa_AKT3_0000500 | Exon-Exon | chr1:243663039-243858955 | chr1:243499737-243695653 | 1295 nt | 0.3946 |
| hsa_AKT3_0000600 | Exon-Exon | chr1:243663039-243859018 | chr1:243499737-243695716 | 1358 nt | 0.3932 |
| hsa_chr1_0714200 | Intergenic-Intergenic | chr1:243666494-243667088 | chr1:243503192-243503786 | 595 nt | 0.4303 |
| hsa_chr1_0714300 | Intergenic-Intergenic | chr1:243667565-243667741 | chr1:243504263-243504439 | 177 nt | 0.3333 |
| hsa_AKT3_0001300 | Exon-Exon | chr1:243667642-243859018 | chr1:243504340-243695716 | 2303 nt | 0.3969 |
| hsa_AKT3_0001500 | Exon-Exon | chr1:243667650-243736350 | chr1:243504348-243573048 | 252 nt | 0.4524 |
| hsa_AKT3_0001400 | Exon-Exon | chr1:243667650-243777041 | chr1:243504348-243613739 | 1714 nt | 0.4032 |
| hsa_AKT3_0001600 | Exon-Exon | chr1:243667650-243859018 | chr1:243504348-243695716 | 126 nt | 0.3730 |
Showing 61 to 70 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].