Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0001900 | Exon-Exon | chr1:243667690-243675728 | chr1:243504388-243512426 | 1050 nt | 0.3962 |
| hsa_AKT3_0002000 | Exon-Exon | chr1:243667690-243716245 | chr1:243504388-243552943 | 1353 nt | 0.3962 |
| hsa_AKT3_0001800 | Exon-Intron | chr1:243667690-243727689 | chr1:243504388-243564387 | 2021 nt | 0.3726 |
| hsa_AKT3_0002100 | Exon-Exon | chr1:243667690-243859018 | chr1:243504388-243695716 | 132 nt | 0.3788 |
| hsa_chr1_0714400 | Intergenic-Intergenic | chr1:243667716-243668408 | chr1:243504414-243505106 | 693 nt | 0.3737 |
| hsa_chr1_0714500 | Intergenic-Intergenic | chr1:243668267-243668408 | chr1:243504965-243505106 | 142 nt | 0.3592 |
| hsa_chr1_0714700 | Intergenic-Intergenic | chr1:243675237-243675721 | chr1:243511935-243512419 | 485 nt | 0.3155 |
| hsa_AKT3_0002500 | Exon-Exon | chr1:243675626-243716079 | chr1:243512324-243552777 | 240 nt | 0.3583 |
| hsa_AKT3_0002600 | Exon-Exon | chr1:243675626-243716245 | chr1:243512324-243552943 | 406 nt | 0.3793 |
| hsa_AKT3_0002700 | Intron-Exon-Intron | chr1:243675626-243727689 | chr1:243512324-243564387 | 103 nt | 0.3204 |
Showing 71 to 80 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].