Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0002800 | Exon-Exon | chr1:243675626-243778463 | chr1:243512324-243615161 | 326 nt | 0.3712 |
| hsa_AKT3_0002900 | Exon-Exon | chr1:243675626-243801044 | chr1:243512324-243637742 | 235 nt | 0.3319 |
| hsa_AKT3_0003000 | Exon-Exon | chr1:243675626-243828185 | chr1:243512324-243664883 | 118 nt | 0.3559 |
| hsa_AKT3_0003100 | Intron-Exon-Intron | chr1:243675626-243835001 | chr1:243512324-243671699 | 191 nt | 0.3560 |
| hsa_AKT3_0003200 | Exon-Exon | chr1:243675626-243859018 | chr1:243512324-243695716 | 132 nt | 0.3561 |
| hsa_chr1_0714800 | Intergenic-Intergenic | chr1:243675635-243675914 | chr1:243512333-243512612 | 280 nt | 0.3643 |
| hsa_AKT3_0003300 | Intron-Intron | chr1:243686611-243690653 | chr1:243523309-243527351 | 250 nt | 0.3000 |
| hsa_AKT3_0003400 | Intron-Exon-Intron | chr1:243686611-243727150 | chr1:243523309-243563848 | 129 nt | 0.4341 |
| hsa_AKT3_0003500 | Intron-Exon-Intron | chr1:243686611-243736350 | chr1:243523309-243573048 | 282 nt | 0.4397 |
| hsa_AKT3_0003600 | Intron-Exon-Intron | chr1:243691056-243778463 | chr1:243527754-243615161 | 141 nt | 0.3972 |
Showing 81 to 90 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].