Basic Information
Symbol
circFOXP1
RNA Class
circRNA
Alias
Forkhead Box P1
HSPC215
HFKH1B
12CC4
QRF1
Fork Head-Related Protein Like B
Mac-1-Regulated Forkhead
Glutamine-Rich Factor 1
Forkhead Box Protein P1
MFH
PAX5/FOXP1 Fusion Protein
Location (GRCh37)
3:71064700-71100343
UCSC Genome Browser
Location (GRCh38)
3:71015549-71051192
Host gene
FOXP1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FOXP1_0008700 | Intron-Intron | chr3:71100059-71100343 | chr3:71050908-71051192 | 285 nt | 0.4035 |
| hsa_FOXP1_0005800 | Exon-Exon | chr3:71064700-71096246 | chr3:71015549-71047095 | 464 nt | 0.5129 |
Forensic Context
A study in mice demonstrated that the circFOXP1 regulates angiogenesis via the miR-544a/FOXP1 and miR-379/FOXP2 axes [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans demonstrated that circFOXP1 hsa_circ_001321 is upregulated in left atrial appendages of patients with nonvalvular persistent atrial fibrillation and is identified as a potential biomarker for this condition [Tian et al. DOI:10.3390/molecules26041155].