Basic Information
Symbol
circGRIN2B
RNA Class
circRNA
Alias
Glutamate Ionotropic Receptor NMDA Type Subunit 2B
GluN2B
NR2B
NMDAR2B
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B
Glutamate [NMDA] Receptor Subunit Epsilon-2
N-Methyl D-Aspartate Receptor Subtype 2B
N-Methyl-D-Aspartate Receptor Subunit 3
Glutamate Receptor Ionotropic, NMDA 2B
HNR3
NR3
Glutamate Receptor Subunit Epsilon-2
GluN2B(Alt_5'UTR)
EIEE27
DEE27
MRD6
Location (GRCh37)
12:13683591-14134510
UCSC Genome Browser
Location (GRCh38)
12:13530657-13981576
Host gene
Grin2b
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_GRIN2B_0000500 | Exon-Exon | chr12:13696664-13696821 | chr12:13543730-13543887 | 158 nt | 0.3861 |
| hsa_chr12_0221200 | Intergenic-Intergenic | chr12:13710349-13710891 | chr12:13557415-13557957 | 543 nt | 0.3628 |
| hsa_GRIN2B_0001400 | Exon-Exon | chr12:13712424-13713113 | chr12:13559490-13560179 | 690 nt | 0.4594 |
| hsa_chr12_0221700 | Intergenic-Intergenic | chr12:13715275-13715537 | chr12:13562341-13562603 | 263 nt | 0.5133 |
| hsa_GRIN2B_0001500 | Exon-Exon | chr12:13715695-13724898 | chr12:13562761-13571964 | 2467 nt | 0.5675 |
| hsa_GRIN2B_0001700 | Exon-Exon | chr12:13716209-13724898 | chr12:13563275-13571964 | 1953 nt | 0.5678 |
| hsa_GRIN2B_0002300 | Exon-Exon | chr12:13761537-13769591 | chr12:13608603-13616657 | 885 nt | 0.5028 |
| hsa_chr12_0222400 | Intergenic-Intergenic | chr12:13794325-13794908 | chr12:13641391-13641974 | 584 nt | 0.3818 |
| hsa_GRIN2B_0003600 | Exon-Exon | chr12:13828679-13906849 | chr12:13675745-13753915 | 714 nt | 0.4818 |
| hsa_GRIN2B_0004000 | Exon-Exon | chr12:13906251-13906849 | chr12:13753317-13753915 | 599 nt | 0.4875 |
Showing 1 to 10 of 78 entries
Forensic Context
A study in rats demonstrated that the circGRIN2B is a heroin-responsive circular RNA significantly upregulated in the orbitofrontal cortex of male rats after heroin self-administration, with validation confirming its upregulation in both sexes and specificity to heroin reward as it was not altered by sucrose self-administration [Floris et al. DOI:10.3390/ijms23031453].