Basic Information
Symbol
circGRIN2B
RNA Class
circRNA
Alias
Glutamate Ionotropic Receptor NMDA Type Subunit 2B
GluN2B
NR2B
NMDAR2B
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B
Glutamate [NMDA] Receptor Subunit Epsilon-2
N-Methyl D-Aspartate Receptor Subtype 2B
N-Methyl-D-Aspartate Receptor Subunit 3
Glutamate Receptor Ionotropic, NMDA 2B
HNR3
NR3
Glutamate Receptor Subunit Epsilon-2
GluN2B(Alt_5'UTR)
EIEE27
DEE27
MRD6
Location (GRCh37)
12:13683591-14134510
UCSC Genome Browser
Location (GRCh38)
12:13530657-13981576
Host gene
Grin2b
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr12_0222100 | Intergenic-Intergenic | chr12:13786816-13805812 | chr12:13633882-13652878 | 250 nt | 0.3520 |
| hsa_GRIN2B_0003300 | Intron-Intron | chr12:13790987-13791240 | chr12:13638053-13638306 | 254 nt | 0.4213 |
| hsa_GRIN2B_0003400 | Intron-Intron | chr12:13792676-13792835 | chr12:13639742-13639901 | 160 nt | 0.3688 |
| hsa_chr12_0222300 | Intergenic-Intergenic | chr12:13794261-13794908 | chr12:13641327-13641974 | 648 nt | 0.3997 |
| hsa_GRIN2B_0003500 | Intron-Intron | chr12:13798712-13799583 | chr12:13645778-13646649 | 872 nt | 0.3807 |
| hsa_GRIN2B_0003700 | Intron-Exon-Intron | chr12:13828679-13968841 | chr12:13675745-13815907 | 115 nt | 0.4522 |
| hsa_GRIN2B_0003800 | Exon-Exon | chr12:13828679-14019160 | chr12:13675745-13866226 | 115 nt | 0.4522 |
| hsa_GRIN2B_0003900 | Intron-Intron | chr12:13833619-13833817 | chr12:13680685-13680883 | 199 nt | 0.4121 |
| hsa_GRIN2B_0004300 | Exon-Exon | chr12:13906251-13906657 | chr12:13753317-13753723 | 407 nt | 0.5012 |
| hsa_GRIN2B_0004400 | Exon-Exon | chr12:13906251-13906720 | chr12:13753317-13753786 | 470 nt | 0.5000 |
Showing 51 to 60 of 78 entries
Forensic Context
A study in rats demonstrated that the circGRIN2B is a heroin-responsive circular RNA significantly upregulated in the orbitofrontal cortex of male rats after heroin self-administration, with validation confirming its upregulation in both sexes and specificity to heroin reward as it was not altered by sucrose self-administration [Floris et al. DOI:10.3390/ijms23031453].