Basic Information
Symbol
circGRIN2B
RNA Class
circRNA
Alias
Glutamate Ionotropic Receptor NMDA Type Subunit 2B
GluN2B
NR2B
NMDAR2B
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B
Glutamate [NMDA] Receptor Subunit Epsilon-2
N-Methyl D-Aspartate Receptor Subtype 2B
N-Methyl-D-Aspartate Receptor Subunit 3
Glutamate Receptor Ionotropic, NMDA 2B
HNR3
NR3
Glutamate Receptor Subunit Epsilon-2
GluN2B(Alt_5'UTR)
EIEE27
DEE27
MRD6
Location (GRCh37)
12:13683591-14134510
UCSC Genome Browser
Location (GRCh38)
12:13530657-13981576
Host gene
Grin2b
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_GRIN2B_0005200 | Intron-Intron | chr12:14013446-14014110 | chr12:13860512-13861176 | 665 nt | 0.4045 |
| hsa_chr12_0222700 | Intergenic-Intergenic | chr12:14014545-14014831 | chr12:13861611-13861897 | 287 nt | 0.4843 |
| hsa_GRIN2B_0005500 | Exon-Intergenic | chr12:14018732-14133290 | chr12:13865798-13980356 | 858 nt | 0.4965 |
| hsa_GRIN2B_0005600 | Intron-Intron | chr12:14032302-14033756 | chr12:13879368-13880822 | 1455 nt | 0.4460 |
| hsa_GRIN2B_0005700 | Intron-Intron | chr12:14072347-14074432 | chr12:13919413-13921498 | 2086 nt | 0.4271 |
| hsa_GRIN2B_0005900 | Intron-Intron | chr12:14120171-14120721 | chr12:13967237-13967787 | 551 nt | 0.4410 |
| hsa_GRIN2B_0006000 | Intron-Intron | chr12:14129680-14129866 | chr12:13976746-13976932 | 187 nt | 0.4118 |
| hsa_GRIN2B_0006200 | Exon-Intergenic | chr12:14132862-14134510 | chr12:13979928-13981576 | 664 nt | 0.4729 |
Showing 71 to 78 of 78 entries
Forensic Context
A study in rats demonstrated that the circGRIN2B is a heroin-responsive circular RNA significantly upregulated in the orbitofrontal cortex of male rats after heroin self-administration, with validation confirming its upregulation in both sexes and specificity to heroin reward as it was not altered by sucrose self-administration [Floris et al. DOI:10.3390/ijms23031453].