Basic Information

Symbol
circHBA1
RNA Class
circRNA
Alias
Hemoglobin Subunit Alpha 1 HBA-T3 Hemoglobin Subunit Alpha Hemoglobin, Alpha 1 Hemoglobin Alpha 1 Globin Chain Hemoglobin Alpha Chain Alpha-2 Globin Chain Alpha Globin Chain Alpha One Globin Delta Globin Alpha-Globin METHBA ECYT7 HBH
Location (GRCh37)
16:223152-227520 UCSC Genome Browser
Location (GRCh38)
16:173153-177521
UCSC Genome Browser Search in Marker Scope
Host gene
HBA1
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HBA1_0000500 Exon-Exon chr16:226928-227520 chr16:176929-177521 444 nt 0.6486
hsa_HBA1_0000600 Exon-Exon chr16:227282-227520 chr16:177283-177521 239 nt 0.6485
hsa_HBA1_0000300 Intergenic-Exon chr16:223152-227505 chr16:173153-177506 250 nt 0.5200
hsa_chr16_0078100 Intergenic-Intergenic chr16:223497-227441 chr16:173498-177442 484 nt 0.6488
hsa_chr16_0078400 Intergenic-Intergenic chr16:223584-227461 chr16:173585-177462 385 nt 0.6545
hsa_HBA1_0000400 Exon-Exon chr16:226706-227481 chr16:176707-177482 251 nt 0.6534
hsa_chr16_0079400 Intergenic-Intergenic chr16:226711-227494 chr16:176712-177495 369 nt 0.6694
hsa_chr16_0079500 Intergenic-Intergenic chr16:226715-227431 chr16:176716-177432 150 nt 0.6467
hsa_chr16_0079600 Intergenic-Intergenic chr16:226952-227434 chr16:176953-177435 334 nt 0.6497
hsa_chr16_0079800 Intergenic-Intergenic chr16:227058-227494 chr16:177059-177495 129 nt 0.6434
Forensic Context

A study in humans demonstrated that circHBA1 is significantly decreased in the peripheral blood of Alzheimer's disease patients and may be used to distinguish them from other dementia cases [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans identified the circHBA1 among 14 circRNA-specific expression patterns in five body fluids—peripheral blood, menstrual blood, saliva, vaginal secretions, and semen—demonstrating its potential for body fluid identification [Li et al. DOI:10.1093/fsr/owad003].