Forensic RNA Knowledge Base

Basic Information

Symbol

circHECTD1

RNA Class

circRNA

Alias

HECT Domain E3 Ubiquitin Protein Ligase 1 KIAA1131 HECT Domain Containing E3 Ubiquitin Protein Ligase 1 E3 Ubiquitin-Protein Ligase HECTD1 HECT Domain-Containing Protein 1 E3 Ligase For Inhibin Receptor EULIR HECT-Type E3 Ubiquitin Transferase HECTD1 EC 2.3.2.26

Location (GRCh37)

14:31569324-31676944 UCSC Genome Browser

Location (GRCh38)

14:31100118-31207738

UCSC Genome Browser Search in Marker Scope

Host gene

HECTD1

Host category

mRNA

Forensic tag(s)

Sudden death from CNS diseases

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_chr14_0145900	Intergenic-Intergenic	chr14:31669923-31670810	chr14:31200717-31201604	888 nt	0.3716
hsa_HECTD1_0043700	Exon-Exon	chr14:31675003-31675163	chr14:31205797-31205957	161 nt	0.4410
hsa_chr14_0146000	Intergenic-Intergenic	chr14:31676703-31676944	chr14:31207497-31207738	242 nt	0.7438

Showing 461 to 463 of 463 entries

Forensic Context

A study in mice demonstrated that the circHECTD1 is increased after stroke, where it sponges miR-142 to derepress TIPARP, promoting astrocyte activation and autophagy [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].