Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0001100 Exon-Exon chr5:78692646-78697878 chr5:79396823-79402055 349 nt 0.4241
hsa_HOMER1_0001200 Exon-Exon chr5:78692646-78734972 chr5:79396823-79439149 489 nt 0.4397
hsa_HOMER1_0001300 Exon-Exon chr5:78692646-78742968 chr5:79396823-79447145 582 nt 0.4313
hsa_HOMER1_0001400 Exon-Exon chr5:78692646-78746944 chr5:79396823-79451121 714 nt 0.4300
hsa_HOMER1_0001500 Exon-Exon chr5:78692646-78752841 chr5:79396823-79457018 871 nt 0.4282
hsa_HOMER1_0002500 Exon-Exon chr5:78697722-78752841 chr5:79401899-79457018 679 nt 0.4462
hsa_HOMER1_0003300 Exon-Exon chr5:78734833-78742968 chr5:79439010-79447145 233 nt 0.4421
hsa_HOMER1_0003400 Exon-Exon chr5:78734833-78746944 chr5:79439010-79451121 365 nt 0.4356
hsa_HOMER1_0003500 Exon-Exon chr5:78734833-78752841 chr5:79439010-79457018 522 nt 0.4310
hsa_HOMER1_0004200 Exon-Exon chr5:78742876-78752841 chr5:79447053-79457018 382 nt 0.4136
Showing 1 to 10 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].