Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0003500 Exon-Exon chr5:78734833-78752841 chr5:79439010-79457018 522 nt 0.4310
hsa_HOMER1_0004200 Exon-Exon chr5:78742876-78752841 chr5:79447053-79457018 382 nt 0.4136
hsa_HOMER1_0004600 Exon-Exon chr5:78746813-78752841 chr5:79450990-79457018 289 nt 0.4221
hsa_HOMER1_0004900 Exon-Exon chr5:78752685-78752841 chr5:79456862-79457018 157 nt 0.4204
hsa_HOMER1_0000200 Intergenic-Exon chr5:78659350-78697878 chr5:79363527-79402055 261 nt 0.4138
hsa_HOMER1_0000400 Intergenic-Exon chr5:78666435-78672020 chr5:79370612-79376197 250 nt 0.2760
hsa_HOMER1_0000600 Intergenic-Exon chr5:78666435-78697878 chr5:79370612-79402055 228 nt 0.4254
hsa_HOMER1_0000700 Intergenic-Exon chr5:78666435-78742968 chr5:79370612-79447145 93 nt 0.3871
hsa_HOMER1_0000500 Intergenic-Exon chr5:78666435-78746944 chr5:79370612-79451121 250 nt 0.2720
hsa_HOMER1_0000800 Intergenic-Exon chr5:78666435-78752841 chr5:79370612-79457018 228 nt 0.3728
Showing 21 to 30 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].