Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0001000 Exon-Exon chr5:78670823-78671905 chr5:79375000-79376082 1083 nt 0.3269
hsa_chr5_0606200 Intergenic-Intergenic chr5:78691623-78691774 chr5:79395800-79395951 152 nt 0.3816
hsa_HOMER1_0001600 Exon-Exon chr5:78692646-78693460 chr5:79396823-79397637 192 nt 0.3646
hsa_HOMER1_0001800 Exon-Exon chr5:78692646-78697873 chr5:79396823-79402050 152 nt 0.5000
hsa_HOMER1_0001900 Exon-Exon chr5:78692646-78742961 chr5:79396823-79447138 81 nt 0.3457
hsa_HOMER1_0002000 Intron-Exon-Intron chr5:78692646-78753191 chr5:79396823-79457368 238 nt 0.3571
hsa_HOMER1_0002100 Intron-Exon-Intron chr5:78692646-78797382 chr5:79396823-79501559 272 nt 0.3787
hsa_HOMER1_0002200 Intron-Exon-Intron chr5:78692646-78802048 chr5:79396823-79506225 111 nt 0.3784
hsa_HOMER1_0001700 Exon-Exon chr5:78692646-78808917 chr5:79396823-79513094 1196 nt 0.4298
hsa_HOMER1_0002300 Exon-Exon chr5:78693350-78697831 chr5:79397527-79402008 221 nt 0.4389
Showing 31 to 40 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].