Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0002400 Exon-Exon chr5:78693350-78752841 chr5:79397527-79457018 790 nt 0.4367
hsa_HOMER1_0002600 Exon-Exon chr5:78697722-78734972 chr5:79401899-79439149 297 nt 0.4882
hsa_HOMER1_0002700 Exon-Exon chr5:78697722-78742968 chr5:79401899-79447145 93 nt 0.3871
hsa_HOMER1_0002800 Exon-Exon chr5:78697722-78746944 chr5:79401899-79451121 297 nt 0.4882
hsa_HOMER1_0002900 Intron-Exon-Intron chr5:78697722-78797382 chr5:79401899-79501559 34 nt 0.2647
hsa_chr5_0606300 Intergenic-Intergenic chr5:78703905-78704242 chr5:79408082-79408419 338 nt 0.3491
hsa_HOMER1_0003000 Intron-Intron chr5:78710150-78730615 chr5:79414327-79434792 250 nt 0.3520
hsa_HOMER1_0003100 Intron-Exon-Intron chr5:78711866-78746944 chr5:79416043-79451121 250 nt 0.2960
hsa_HOMER1_0003200 Intron-Exon-Intron chr5:78732786-78746944 chr5:79436963-79451121 2412 nt 0.3458
hsa_HOMER1_0003900 Intron-Exon-Intron chr5:78734833-78780658 chr5:79439010-79484835 233 nt 0.4421
Showing 41 to 50 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].