Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0004000 Intron-Exon-Intron chr5:78734833-78797382 chr5:79439010-79501559 556 nt 0.4209
hsa_HOMER1_0003600 Intron-Exon-Intron chr5:78734833-78802048 chr5:79439010-79506225 250 nt 0.3800
hsa_HOMER1_0003700 Intron-Exon-Intron chr5:78734833-78807758 chr5:79439010-79511935 250 nt 0.3360
hsa_HOMER1_0003800 Exon-Exon chr5:78734833-78808917 chr5:79439010-79513094 847 nt 0.4321
hsa_chr5_0606400 Intergenic-Intergenic chr5:78736667-78736918 chr5:79440844-79441095 252 nt 0.5119
hsa_HOMER1_0004100 Intron-Intron chr5:78739915-78740140 chr5:79444092-79444317 226 nt 0.4469
hsa_HOMER1_0004300 Exon-Exon chr5:78742876-78746944 chr5:79447053-79451121 225 nt 0.4089
hsa_HOMER1_0004400 Exon-Exon chr5:78742876-78752727 chr5:79447053-79456904 268 nt 0.3993
hsa_HOMER1_0004500 Intron-Exon-Intron chr5:78742876-78797382 chr5:79447053-79501559 127 nt 0.3543
hsa_chr5_0606600 Intergenic-Intergenic chr5:78743531-78743907 chr5:79447708-79448084 377 nt 0.3316
Showing 51 to 60 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].