Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0004700 Intron-Exon-Intron chr5:78746813-78752868 chr5:79450990-79457045 316 nt 0.4241
hsa_HOMER1_0004800 Intron-Exon-Intron chr5:78746813-78797382 chr5:79450990-79501559 132 nt 0.4242
hsa_chr5_0606700 Intergenic-Intergenic chr5:78759435-78759659 chr5:79463612-79463836 225 nt 0.4000
hsa_HOMER1_0005000 Intron-Intron chr5:78777533-78781737 chr5:79481710-79485914 250 nt 0.3560
hsa_HOMER1_0005100 Intron-Intron chr5:78778561-78792164 chr5:79482738-79496341 250 nt 0.3840
hsa_chr5_0606800 Intergenic-Intergenic chr5:78793130-78793837 chr5:79497307-79498014 708 nt 0.4407
hsa_HOMER1_0005200 Intron-Intron chr5:78794262-78794410 chr5:79498439-79498587 149 nt 0.3826
hsa_chr5_0606900 Intergenic-Intergenic chr5:78802033-78802971 chr5:79506210-79507148 939 nt 0.4207
hsa_chr5_0607000 Intergenic-Intergenic chr5:78802040-78802971 chr5:79506217-79507148 932 nt 0.4206
hsa_HOMER1_0000200 Intergenic-Exon chr5:78659350-78697878 chr5:79363527-79402055 261 nt 0.4138
Showing 61 to 70 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].