Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0000400 Intergenic-Exon chr5:78666435-78672020 chr5:79370612-79376197 250 nt 0.2760
hsa_HOMER1_0000600 Intergenic-Exon chr5:78666435-78697878 chr5:79370612-79402055 228 nt 0.4254
hsa_HOMER1_0000700 Intergenic-Exon chr5:78666435-78742968 chr5:79370612-79447145 93 nt 0.3871
hsa_HOMER1_0000500 Intergenic-Exon chr5:78666435-78746944 chr5:79370612-79451121 250 nt 0.2720
hsa_HOMER1_0000800 Intergenic-Exon chr5:78666435-78752841 chr5:79370612-79457018 228 nt 0.3728
hsa_HOMER1_0001000 Exon-Exon chr5:78670823-78671905 chr5:79375000-79376082 1083 nt 0.3269
hsa_chr5_0606200 Intergenic-Intergenic chr5:78691623-78691774 chr5:79395800-79395951 152 nt 0.3816
hsa_HOMER1_0001600 Exon-Exon chr5:78692646-78693460 chr5:79396823-79397637 192 nt 0.3646
hsa_HOMER1_0001800 Exon-Exon chr5:78692646-78697873 chr5:79396823-79402050 152 nt 0.5000
hsa_HOMER1_0001900 Exon-Exon chr5:78692646-78742961 chr5:79396823-79447138 81 nt 0.3457
Showing 71 to 80 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].