Basic Information

Symbol
circHOMER1
RNA Class
circRNA
Alias
Homer Scaffold Protein 1 SYN47 Ves-1 Homer Scaffolding Protein 1 Homer Protein Homolog 1 HOMER-1B Homer-1 Homer, Neuronal Immediate Early Gene, 1 Homer Homolog 1 (Drosophila) Homer Homolog 1 HOMER1A HOMER1B HOMER1C HOMER
Location (GRCh37)
5:78659350-78808917 UCSC Genome Browser
Location (GRCh38)
5:79363527-79513094
UCSC Genome Browser Search in Marker Scope
Host gene
HOMER1
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_HOMER1_0002000 Intron-Exon-Intron chr5:78692646-78753191 chr5:79396823-79457368 238 nt 0.3571
hsa_HOMER1_0002100 Intron-Exon-Intron chr5:78692646-78797382 chr5:79396823-79501559 272 nt 0.3787
hsa_HOMER1_0002200 Intron-Exon-Intron chr5:78692646-78802048 chr5:79396823-79506225 111 nt 0.3784
hsa_HOMER1_0001700 Exon-Exon chr5:78692646-78808917 chr5:79396823-79513094 1196 nt 0.4298
hsa_HOMER1_0002300 Exon-Exon chr5:78693350-78697831 chr5:79397527-79402008 221 nt 0.4389
hsa_HOMER1_0002400 Exon-Exon chr5:78693350-78752841 chr5:79397527-79457018 790 nt 0.4367
hsa_HOMER1_0002600 Exon-Exon chr5:78697722-78734972 chr5:79401899-79439149 297 nt 0.4882
hsa_HOMER1_0002700 Exon-Exon chr5:78697722-78742968 chr5:79401899-79447145 93 nt 0.3871
hsa_HOMER1_0002800 Exon-Exon chr5:78697722-78746944 chr5:79401899-79451121 297 nt 0.4882
hsa_HOMER1_0002900 Intron-Exon-Intron chr5:78697722-78797382 chr5:79401899-79501559 34 nt 0.2647
Showing 81 to 90 of 114 entries
Forensic Context

A study in mice demonstrated that the circHOMER1 is upregulated in primary cortical neurons and multiple brain regions, including the hippocampus, prefrontal cortex, ventral tegmental area, and nucleus accumbens, following methamphetamine exposure, where it is associated with methamphetamine-induced toxicity and conditioned place preference scores [Daws et al. DOI:10.1016/j.mcn.2023.103841]. The circHOMER1 is recognized as a synaptically-enriched circRNA that modulates structural changes at synapses during neuronal plasticity and development [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans and mice demonstrated that circHomer 1, a circular RNA, regulates neuronal plasticity and structural changes in the synapse during development [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].