Forensic RNA Knowledge Base

Basic Information

Symbol

circIRF4

RNA Class

circRNA

Alias

Interferon Regulatory Factor 4 LSIRF MUM1 Lymphocyte-Specific Interferon Regulatory Factor Multiple Myeloma Oncogene 1 NF-EM5 IMD131 SHEP8 IRF-4

Location (GRCh37)

6:393098-393368 UCSC Genome Browser

Location (GRCh38)

6:393098-393368

UCSC Genome Browser Search in Marker Scope

Host gene

IRF4

Host category

mRNA

Forensic tag(s)

Other applications

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_IRF4_0000100	Exon-Exon	chr6:393098-393368	chr6:393098-393368	271 nt	0.6937

Forensic Context

A study in humans demonstrated that circIRF4 is significantly increased in serum exosomes of patients with metastatic pancreatic cancer, where its levels correlate with TNM stages and poor prognosis [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of the literature indicates that the circIRF4 is down-regulated in osteosarcoma [Di Agostino et al. DOI:10.3389/fcell.2020.00389].