Basic Information

Symbol
circKLHL1
RNA Class
circRNA
Alias
Kelch Like Family Member 1 Kelch-Like Protein 1 KIAA1490 MRP2 Mayven-Related Protein 2 FLJ30047 Kelch (Drosophila)-Like 1 Kelch-Like 1 (Drosophila)
Location (GRCh37)
13:70281757-70681526 UCSC Genome Browser
Location (GRCh38)
13:69707625-70107394
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL1_0000300 Exon-Exon chr13:70293501-70514368 chr13:69719369-69940236 1198 nt 0.4349
hsa_KLHL1_0000500 Exon-Exon chr13:70314526-70314688 chr13:69740394-69740556 163 nt 0.4724
hsa_KLHL1_0000600 Exon-Exon chr13:70314526-70413294 chr13:69740394-69839162 575 nt 0.4157
hsa_KLHL1_0000700 Exon-Exon chr13:70314526-70549934 chr13:69740394-69975802 1305 nt 0.4330
hsa_KLHL1_0001200 Exon-Exon chr13:70370870-70413294 chr13:69796738-69839162 412 nt 0.3932
hsa_KLHL1_0001300 Exon-Exon chr13:70370870-70456627 chr13:69796738-69882495 625 nt 0.4048
hsa_KLHL1_0002000 Exon-Exon chr13:70413108-70413294 chr13:69838976-69839162 187 nt 0.3583
hsa_KLHL1_0002100 Exon-Exon chr13:70413108-70456627 chr13:69838976-69882495 400 nt 0.3950
hsa_KLHL1_0002700 Exon-Exon chr13:70456415-70535576 chr13:69882283-69961444 547 nt 0.4534
hsa_KLHL1_0002800 Exon-Exon chr13:70456415-70549934 chr13:69882283-69975802 730 nt 0.4466
Showing 1 to 10 of 64 entries
Forensic Context

A study in humans identified the circKLHL1 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically noted [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of literature indicates that the circKLHL1 is a synaptically-enriched circular RNA abundant in the dendritic arbor of neurons, suggesting a role in synaptic function [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].