Basic Information

Symbol
circKLHL1
RNA Class
circRNA
Alias
Kelch Like Family Member 1 Kelch-Like Protein 1 KIAA1490 MRP2 Mayven-Related Protein 2 FLJ30047 Kelch (Drosophila)-Like 1 Kelch-Like 1 (Drosophila)
Location (GRCh37)
13:70281757-70681526 UCSC Genome Browser
Location (GRCh38)
13:69707625-70107394
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL1_0003300 Intron-Exon-Intron chr13:70512556-70549934 chr13:69938424-69975802 2133 nt 0.3418
hsa_KLHL1_0003400 Exon-Exon chr13:70514172-70514368 chr13:69940040-69940236 197 nt 0.4822
hsa_KLHL1_0003500 Exon-Exon chr13:70514172-70535576 chr13:69940040-69961444 334 nt 0.4701
hsa_KLHL1_0003600 Exon-Exon chr13:70514172-70549934 chr13:69940040-69975802 517 nt 0.4545
hsa_KLHL1_0003700 Intron-Exon-Intron chr13:70514172-70552290 chr13:69940040-69978158 2873 nt 0.3178
hsa_KLHL1_0003800 Intron-Exon-Intron chr13:70514172-70568930 chr13:69940040-69994798 250 nt 0.3360
hsa_KLHL1_0004600 Exon-Exon chr13:70535440-70549898 chr13:69961308-69975766 284 nt 0.4296
hsa_KLHL1_0004700 Exon-Exon chr13:70535440-70549934 chr13:69961308-69975802 320 nt 0.4375
hsa_KLHL1_0004800 Intron-Exon-Intron chr13:70535440-70568930 chr13:69961308-69994798 250 nt 0.3280
hsa_KLHL1_0000100 Exon-Exon chr13:70281757-70371094 chr13:69707625-69796962 773 nt 0.4502
Showing 11 to 20 of 64 entries
Forensic Context

A study in humans identified the circKLHL1 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically noted [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of literature indicates that the circKLHL1 is a synaptically-enriched circular RNA abundant in the dendritic arbor of neurons, suggesting a role in synaptic function [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].