Basic Information

Symbol
circKLHL1
RNA Class
circRNA
Alias
Kelch Like Family Member 1 Kelch-Like Protein 1 KIAA1490 MRP2 Mayven-Related Protein 2 FLJ30047 Kelch (Drosophila)-Like 1 Kelch-Like 1 (Drosophila)
Location (GRCh37)
13:70281757-70681526 UCSC Genome Browser
Location (GRCh38)
13:69707625-70107394
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL1_0000200 Exon-Exon chr13:70281757-70413294 chr13:69707625-69839162 960 nt 0.4323
hsa_KLHL1_0000400 Exon-Exon chr13:70293501-70413294 chr13:69719369-69839162 788 nt 0.4251
hsa_KLHL1_0000800 Exon-Exon chr13:70314526-70456627 chr13:69740394-69882495 788 nt 0.4188
hsa_KLHL1_0000900 Intron-Exon-Intron chr13:70341814-70514368 chr13:69767682-69940236 250 nt 0.3320
hsa_KLHL1_0001000 Intron-Exon-Intron chr13:70364867-70371094 chr13:69790735-69796962 250 nt 0.3840
hsa_KLHL1_0001100 Intron-Exon-Intron chr13:70364867-70549934 chr13:69790735-69975802 148 nt 0.5135
hsa_KLHL1_0001400 Intron-Exon-Intron chr13:70370870-70377942 chr13:69796738-69803810 250 nt 0.3400
hsa_KLHL1_0001500 Intron-Exon-Intron chr13:70370870-70380716 chr13:69796738-69806584 250 nt 0.3640
hsa_KLHL1_0001600 Exon-Exon chr13:70370870-70514368 chr13:69796738-69940236 822 nt 0.4234
hsa_KLHL1_0001700 Exon-Exon chr13:70370870-70549934 chr13:69796738-69975802 545 nt 0.4312
Showing 21 to 30 of 64 entries
Forensic Context

A study in humans identified the circKLHL1 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically noted [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of literature indicates that the circKLHL1 is a synaptically-enriched circular RNA abundant in the dendritic arbor of neurons, suggesting a role in synaptic function [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].