Basic Information

Symbol
circKLHL1
RNA Class
circRNA
Alias
Kelch Like Family Member 1 Kelch-Like Protein 1 KIAA1490 MRP2 Mayven-Related Protein 2 FLJ30047 Kelch (Drosophila)-Like 1 Kelch-Like 1 (Drosophila)
Location (GRCh37)
13:70281757-70681526 UCSC Genome Browser
Location (GRCh38)
13:69707625-70107394
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL1_0001800 Intron-Exon-Intron chr13:70370870-70568930 chr13:69796738-69994798 419 nt 0.4248
hsa_KLHL1_0001900 Intron-Intron chr13:70407997-70408347 chr13:69833865-69834215 351 nt 0.4131
hsa_KLHL1_0002200 Exon-Exon chr13:70413108-70456604 chr13:69838976-69882472 377 nt 0.4005
hsa_KLHL1_0002300 Exon-Exon chr13:70413108-70514368 chr13:69838976-69940236 197 nt 0.4822
hsa_KLHL1_0002400 Exon-Exon chr13:70413108-70535576 chr13:69838976-69961444 137 nt 0.4526
hsa_KLHL1_0002500 Exon-Exon chr13:70413108-70549934 chr13:69838976-69975802 193 nt 0.3679
hsa_KLHL1_0002600 Intron-Exon-Intron chr13:70413108-70568930 chr13:69838976-69994798 99 nt 0.3838
hsa_KLHL1_0003000 Exon-Exon chr13:70456415-70514368 chr13:69882283-69940236 410 nt 0.4537
hsa_KLHL1_0002900 Intron-Exon-Intron chr13:70456415-70545073 chr13:69882283-69970941 250 nt 0.3560
hsa_KLHL1_0003100 Intron-Exon-Intron chr13:70456415-70568930 chr13:69882283-69994798 105 nt 0.4000
Showing 31 to 40 of 64 entries
Forensic Context

A study in humans identified the circKLHL1 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically noted [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of literature indicates that the circKLHL1 is a synaptically-enriched circular RNA abundant in the dendritic arbor of neurons, suggesting a role in synaptic function [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].