Basic Information
Symbol
circKLHL1
RNA Class
circRNA
Alias
Kelch Like Family Member 1
Kelch-Like Protein 1
KIAA1490
MRP2
Mayven-Related Protein 2
FLJ30047
Kelch (Drosophila)-Like 1
Kelch-Like 1 (Drosophila)
Location (GRCh37)
13:70281757-70681526
UCSC Genome Browser
Location (GRCh38)
13:69707625-70107394
Host gene
KLHL1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_KLHL1_0005800 | Intron-Intron | chr13:70665589-70665776 | chr13:70091457-70091644 | 188 nt | 0.3777 |
| hsa_KLHL1_0005900 | Intron-Intron | chr13:70665610-70665749 | chr13:70091478-70091617 | 140 nt | 0.3500 |
| hsa_chr13_0246300 | Intergenic-Intergenic | chr13:70678294-70678435 | chr13:70104162-70104303 | 142 nt | 0.3310 |
| hsa_KLHL1_0006000 | Exon-Exon | chr13:70681335-70681526 | chr13:70107203-70107394 | 192 nt | 0.5833 |
Showing 61 to 64 of 64 entries
Forensic Context
A study in humans identified the circKLHL1 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically noted [Misir et al. DOI:10.1038/s41418-022-00948-7]. A review of literature indicates that the circKLHL1 is a synaptically-enriched circular RNA abundant in the dendritic arbor of neurons, suggesting a role in synaptic function [Suresh L. Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].