Basic Information

Symbol
circKLHL2
RNA Class
circRNA
Alias
Kelch Like Family Member 2 MAV Actin-Binding Protein Mayven Kelch-Like Protein 2 Mayven Kelch (Drosophila)-Like 2 (Mayven) Kelch-Like 2, Mayven (Drosophila) Kelch-Like 2, Mayven ABP-KELCH
Location (GRCh37)
4:166131171-166239121 UCSC Genome Browser
Location (GRCh38)
4:165210019-165317969
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL2
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases Cause of death analysis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL2_0000100 Exon-Exon chr4:166131171-166184511 chr4:165210019-165263359 680 nt 0.4368
hsa_KLHL2_0000200 Exon-Exon chr4:166131171-166220808 chr4:165210019-165299656 1057 nt 0.4352
hsa_KLHL2_0001200 Exon-Exon chr4:166141086-166150065 chr4:165219934-165228913 233 nt 0.4206
hsa_KLHL2_0001300 Exon-Exon chr4:166141086-166160051 chr4:165219934-165238899 355 nt 0.4169
hsa_KLHL2_0001400 Exon-Exon chr4:166141086-166184511 chr4:165219934-165263359 518 nt 0.4344
hsa_KLHL2_0001500 Exon-Exon chr4:166141086-166215620 chr4:165219934-165294468 628 nt 0.4236
hsa_KLHL2_0001600 Exon-Exon chr4:166141086-166226877 chr4:165219934-165305725 1013 nt 0.4452
hsa_KLHL2_0001700 Exon-Exon chr4:166141086-166235318 chr4:165219934-165314166 1583 nt 0.4479
hsa_KLHL2_0001800 Exon-Exon chr4:166141086-166239121 chr4:165219934-165317969 1727 nt 0.4459
hsa_KLHL2_0002200 Exon-Exon chr4:166149959-166150065 chr4:165228807-165228913 107 nt 0.4393
Showing 1 to 10 of 64 entries
Forensic Context

A study in humans identified the circKLHL2 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in mice and human patients demonstrated that the circKLHL2 may expedite sepsis-induced acute lung injury by adjusting the miR-29b-3p/ROCK axis [Xu et al. DOI:10.1080/01902148.2024.2429184].