Basic Information

Symbol
circKLHL2
RNA Class
circRNA
Alias
Kelch Like Family Member 2 MAV Actin-Binding Protein Mayven Kelch-Like Protein 2 Mayven Kelch (Drosophila)-Like 2 (Mayven) Kelch-Like 2, Mayven (Drosophila) Kelch-Like 2, Mayven ABP-KELCH
Location (GRCh37)
4:166131171-166239121 UCSC Genome Browser
Location (GRCh38)
4:165210019-165317969
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL2
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases Cause of death analysis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL2_0002300 Exon-Exon chr4:166149959-166231902 chr4:165228807-165310750 1085 nt 0.4571
hsa_KLHL2_0002700 Exon-Exon chr4:166159930-166184511 chr4:165238778-165263359 285 nt 0.4456
hsa_KLHL2_0003100 Exon-Exon chr4:166184349-166218877 chr4:165263197-165297725 390 nt 0.4359
hsa_KLHL2_0003200 Exon-Exon chr4:166184349-166220808 chr4:165263197-165299656 540 nt 0.4444
hsa_KLHL2_0003800 Exon-Exon chr4:166215511-166220808 chr4:165294359-165299656 377 nt 0.4324
hsa_KLHL2_0004400 Exon-Exon chr4:166220659-166231902 chr4:165299507-165310750 466 nt 0.4914
hsa_KLHL2_0004800 Exon-Exon chr4:166226760-166231902 chr4:165305608-165310750 316 nt 0.5032
hsa_KLHL2_0004900 Exon-Exon chr4:166226760-166232717 chr4:165305608-165311565 418 nt 0.4880
hsa_KLHL2_0005300 Exon-Exon chr4:166231705-166231902 chr4:165310553-165310750 198 nt 0.4848
hsa_KLHL2_0005600 Exon-Exon chr4:166232616-166234518 chr4:165311464-165313366 231 nt 0.4502
Showing 11 to 20 of 64 entries
Forensic Context

A study in humans identified the circKLHL2 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in mice and human patients demonstrated that the circKLHL2 may expedite sepsis-induced acute lung injury by adjusting the miR-29b-3p/ROCK axis [Xu et al. DOI:10.1080/01902148.2024.2429184].