Basic Information

Symbol
circKLHL2
RNA Class
circRNA
Alias
Kelch Like Family Member 2 MAV Actin-Binding Protein Mayven Kelch-Like Protein 2 Mayven Kelch (Drosophila)-Like 2 (Mayven) Kelch-Like 2, Mayven (Drosophila) Kelch-Like 2, Mayven ABP-KELCH
Location (GRCh37)
4:166131171-166239121 UCSC Genome Browser
Location (GRCh38)
4:165210019-165317969
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL2
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases Cause of death analysis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL2_0002000 Intron-Exon-Intron chr4:166141086-166198695 chr4:165219934-165277543 126 nt 0.4048
hsa_KLHL2_0002100 Exon-Exon chr4:166141086-166220808 chr4:165219934-165299656 150 nt 0.4667
hsa_KLHL2_0002400 Exon-Exon chr4:166149959-166160051 chr4:165228807-165238899 229 nt 0.4236
hsa_KLHL2_0002600 Exon-Exon chr4:166149959-166184511 chr4:165228807-165263359 270 nt 0.4593
hsa_KLHL2_0002500 Exon-Exon chr4:166149959-166220808 chr4:165228807-165299656 769 nt 0.4382
hsa_KLHL2_0002800 Intron-Exon-Intron chr4:166159930-166161616 chr4:165238778-165240464 1687 nt 0.3651
hsa_KLHL2_0002900 Exon-Exon chr4:166159930-166226877 chr4:165238778-165305725 780 nt 0.4526
hsa_KLHL2_0003000 Intron-Intron chr4:166170109-166171534 chr4:165248957-165250382 1426 nt 0.4257
hsa_chr4_0257200 Intergenic-Intergenic chr4:166174167-166175541 chr4:165253015-165254389 1375 nt 0.3796
hsa_chr4_0257300 Intergenic-Intergenic chr4:166176897-166177057 chr4:165255745-165255905 161 nt 0.4286
Showing 31 to 40 of 64 entries
Forensic Context

A study in humans identified the circKLHL2 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in mice and human patients demonstrated that the circKLHL2 may expedite sepsis-induced acute lung injury by adjusting the miR-29b-3p/ROCK axis [Xu et al. DOI:10.1080/01902148.2024.2429184].