Basic Information

Symbol
circKLHL2
RNA Class
circRNA
Alias
Kelch Like Family Member 2 MAV Actin-Binding Protein Mayven Kelch-Like Protein 2 Mayven Kelch (Drosophila)-Like 2 (Mayven) Kelch-Like 2, Mayven (Drosophila) Kelch-Like 2, Mayven ABP-KELCH
Location (GRCh37)
4:166131171-166239121 UCSC Genome Browser
Location (GRCh38)
4:165210019-165317969
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL2
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases Cause of death analysis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_KLHL2_0003300 Intron-Exon-Intron chr4:166184349-166196937 chr4:165263197-165275785 250 nt 0.3920
hsa_KLHL2_0003400 Intron-Exon-Intron chr4:166198641-166215620 chr4:165277489-165294468 250 nt 0.2840
hsa_KLHL2_0003500 Intron-Intron chr4:166207123-166207351 chr4:165285971-165286199 229 nt 0.4061
hsa_KLHL2_0003600 Intron-Intron chr4:166211565-166211843 chr4:165290413-165290691 279 nt 0.2975
hsa_KLHL2_0003700 Intron-Exon-Intron chr4:166213510-166220808 chr4:165292358-165299656 2378 nt 0.3970
hsa_KLHL2_0003900 Exon-Exon chr4:166215511-166218877 chr4:165294359-165297725 227 nt 0.4097
hsa_KLHL2_0004100 Exon-Exon chr4:166215511-166226877 chr4:165294359-165305725 268 nt 0.4963
hsa_KLHL2_0004200 Exon-Exon chr4:166215511-166231902 chr4:165294359-165310750 260 nt 0.4269
hsa_KLHL2_0004000 Exon-Exon chr4:166215511-166235318 chr4:165294359-165314166 1065 nt 0.4545
hsa_KLHL2_0004300 Exon-Exon chr4:166218761-166231902 chr4:165297609-165310750 583 nt 0.4820
Showing 41 to 50 of 64 entries
Forensic Context

A study in humans identified the circKLHL2 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in mice and human patients demonstrated that the circKLHL2 may expedite sepsis-induced acute lung injury by adjusting the miR-29b-3p/ROCK axis [Xu et al. DOI:10.1080/01902148.2024.2429184].