Basic Information

Symbol
circKLHL2
RNA Class
circRNA
Alias
Kelch Like Family Member 2 MAV Actin-Binding Protein Mayven Kelch-Like Protein 2 Mayven Kelch (Drosophila)-Like 2 (Mayven) Kelch-Like 2, Mayven (Drosophila) Kelch-Like 2, Mayven ABP-KELCH
Location (GRCh37)
4:166131171-166239121 UCSC Genome Browser
Location (GRCh38)
4:165210019-165317969
UCSC Genome Browser Search in Marker Scope
Host gene
KLHL2
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases Cause of death analysis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr4_0257400 Intergenic-Intergenic chr4:166218791-166220799 chr4:165297639-165299647 228 nt 0.4649
hsa_chr4_0257500 Intergenic-Intergenic chr4:166222245-166222702 chr4:165301093-165301550 458 nt 0.3253
hsa_KLHL2_0004500 Intron-Exon-Intron chr4:166224089-166226877 chr4:165302937-165305725 2789 nt 0.3937
hsa_KLHL2_0004600 Intron-Exon-Intron chr4:166224132-166226877 chr4:165302980-165305725 2746 nt 0.3948
hsa_KLHL2_0004700 Intron-Exon-Intron chr4:166224926-166228246 chr4:165303774-165307094 250 nt 0.4320
hsa_KLHL2_0005100 Exon-Exon chr4:166226760-166235318 chr4:165305608-165314166 339 nt 0.4543
hsa_KLHL2_0005200 Exon-Exon chr4:166226834-166231740 chr4:165305682-165310588 80 nt 0.5500
hsa_KLHL2_0005400 Exon-Exon chr4:166231705-166232717 chr4:165310553-165311565 300 nt 0.4700
hsa_KLHL2_0005500 Exon-Exon chr4:166231705-166235318 chr4:165310553-165314166 441 nt 0.4512
hsa_KLHL2_0005700 Exon-Exon chr4:166234390-166238995 chr4:165313238-165317843 141 nt 0.4113
Showing 51 to 60 of 64 entries
Forensic Context

A study in humans identified the circKLHL2 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in mice and human patients demonstrated that the circKLHL2 may expedite sepsis-induced acute lung injury by adjusting the miR-29b-3p/ROCK axis [Xu et al. DOI:10.1080/01902148.2024.2429184].