Basic Information
Symbol
circLACTB
RNA Class
circRNA
Alias
Lactamase Beta
MRPL56
Serine Beta-Lactamase-Like Protein LACTB, Mitochondrial
Serine Beta-Lactamase-Like Protein, Mitochondrial
FLJ14902
Mitochondrial 39S Ribosomal Protein L56
Mitochondrial Ribosomal Protein L56
EC 3.4.-.-
G24
Location (GRCh37)
15:63419058-63421849
UCSC Genome Browser
Location (GRCh38)
15:63126859-63129650
Host gene
LACTB
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Cause of death analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_LACTB_0000500 | Exon-Exon | chr15:63419058-63421849 | chr15:63126859-63129650 | 694 nt | 0.3617 |
Forensic Context
A study in humans demonstrated that circLACTB is significantly decreased in peripheral blood of Alzheimer's disease patients and may distinguish them from other dementia types [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans identified the circLACTB as an exonic circRNA that is significantly up-regulated and co-differentially expressed in both lung tissue and plasma from patients with sepsis-induced acute respiratory distress syndrome compared to controls [Guo et al. DOI:10.1016/j.lfs.2021.119566].