Basic Information

Symbol
circLMTK2
RNA Class
circRNA
Alias
Lemur Tyrosine Kinase 2 AATYK2 KPI2 LMR2 BREK KIAA1079 PPP1R100 KPI-2 Cprk Protein Phosphatase 1, Regulatory Subunit 100 Apoptosis-Associated Tyrosine Kinase 2 Serine/Threonine-Protein Kinase LMTK2 Serine/Threonine-Protein Kinase KPI-2 Kinase/Phosphatase/Inhibitor 2 CDK5/P35-Regulated Kinase Brain-Enriched Kinase EC 2.7.11.1 HBREK Cyclin-Dependent Kinase 5/P35-Regulated Kinase EC 2.7.11 CPRK
Location (GRCh37)
7:97736281-97838944 UCSC Genome Browser
Location (GRCh38)
Host gene
LMTK2
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses Postmortem interval inference Tissue/body fluid identification
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr7_0665800 Intergenic-Intergenic chr7:97828747-97829154 chr7:98199435-98199842 408 nt 0.4926
hsa_LMTK2_0005500 Exon-Exon chr7:97832886-97833498 chr7:98203574-98204186 376 nt 0.6064
hsa_chr7_0665900 Intergenic-Intergenic chr7:97836252-97836543 chr7:98206940-98207231 292 nt 0.5925
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Forensic Context

A study in rats demonstrated that the circLMTK2 was identified as a putative heroin-associated biomarker in a microarray analysis of orbitofrontal cortex tissue following heroin self-administration, though its amplification was undetectable in subsequent validation qPCR [Floris et al. DOI:10.3390/ijms23031453]. CircRNAs, as a class, exhibit stability in postmortem tissues and body fluids, supporting their potential for forensic applications such as postmortem interval estimation and body fluid identification [Tian et al. DOI:10.3390/molecules26041155].