Basic Information
Symbol
circLRP1B
RNA Class
circRNA
Alias
LDL Receptor Related Protein 1B
LRP-DIT
LRPDIT
Low Density Lipoprotein Receptor-Related Protein 1B
Low-Density Lipoprotein Receptor-Related Protein 1B
LRP-Deleted In Tumors
LRP-1B
Low Density Lipoprotein Receptor Related Protein-Deleted In Tumor
Low-Density Lipoprotein Receptor-Related Protein-Deleted In Tumor
Low Density Lipoprotein-Related Protein 1B (Deleted In Tumors)
EC 3.4.21.9
EC 1.1.1.94
Location (GRCh37)
2:140989360-142889270
UCSC Genome Browser
Location (GRCh38)
2:140231791-142131701
Host gene
LRP1B
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_LRP1B_0010800 | Exon-Exon | chr2:141143465-141202248 | chr2:140385896-140444679 | 471 nt | 0.4395 |
| hsa_chr2_0149100 | Intergenic-Intergenic | chr2:141143561-141202203 | chr2:140385992-140444634 | 330 nt | 0.4424 |
| hsa_LRP1B_0010900 | Intron-Exon-Intron | chr2:141159884-141215220 | chr2:140402315-140457651 | 291 nt | 0.4777 |
| hsa_LRP1B_0011000 | Intron-Intron | chr2:141168724-141169362 | chr2:140411155-140411793 | 639 nt | 0.2645 |
| hsa_LRP1B_0011100 | Intron-Exon-Intron | chr2:141178565-141232906 | chr2:140420996-140475337 | 250 nt | 0.3560 |
| hsa_LRP1B_0011200 | Intron-Intron | chr2:141194422-141194870 | chr2:140436853-140437301 | 449 nt | 0.4388 |
| hsa_LRP1B_0011300 | Intron-Exon-Intron | chr2:141199879-141202248 | chr2:140442310-140444679 | 551 nt | 0.4319 |
| hsa_LRP1B_0011400 | Intron-Exon-Intron | chr2:141199879-141232906 | chr2:140442310-140475337 | 1183 nt | 0.4294 |
| hsa_LRP1B_0012400 | Exon-Exon | chr2:141200073-141232771 | chr2:140442504-140475202 | 854 nt | 0.4461 |
| hsa_LRP1B_0012500 | Exon-Exon | chr2:141200073-141250262 | chr2:140442504-140492693 | 126 nt | 0.4841 |
Showing 191 to 200 of 509 entries
Forensic Context
A study in mice demonstrated that the circLRP1B is upregulated following traumatic brain injury, and its inhibition reduces inflammation and autophagy by regulating the miR-27a-3p/Dram2 signaling pathway [Li et al. DOI:10.1016/j.neuint.2023.105643].