Basic Information
Symbol
circLRP1B
RNA Class
circRNA
Alias
LDL Receptor Related Protein 1B
LRP-DIT
LRPDIT
Low Density Lipoprotein Receptor-Related Protein 1B
Low-Density Lipoprotein Receptor-Related Protein 1B
LRP-Deleted In Tumors
LRP-1B
Low Density Lipoprotein Receptor Related Protein-Deleted In Tumor
Low-Density Lipoprotein Receptor-Related Protein-Deleted In Tumor
Low Density Lipoprotein-Related Protein 1B (Deleted In Tumors)
EC 3.4.21.9
EC 1.1.1.94
Location (GRCh37)
2:140989360-142889270
UCSC Genome Browser
Location (GRCh38)
2:140231791-142131701
Host gene
LRP1B
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_LRP1B_0038600 | Intron-Exon-Intron | chr2:141945990-141949578 | chr2:141188421-141192009 | 250 nt | 0.3000 |
| hsa_LRP1B_0038900 | Exon-Exon | chr2:141945990-142004923 | chr2:141188421-141247354 | 550 nt | 0.3818 |
| hsa_LRP1B_0038700 | Intron-Exon-Intron | chr2:141945990-142015048 | chr2:141188421-141257479 | 250 nt | 0.3400 |
| hsa_LRP1B_0039000 | Intron-Exon-Intron | chr2:141945990-142080047 | chr2:141188421-141322478 | 163 nt | 0.4417 |
| hsa_LRP1B_0039100 | Intron-Intron | chr2:141966411-141969935 | chr2:141208842-141212366 | 250 nt | 0.2920 |
| hsa_LRP1B_0039200 | Intron-Exon-Intron | chr2:141978065-142012210 | chr2:141220496-141254641 | 250 nt | 0.3360 |
| hsa_LRP1B_0039400 | Intron-Exon-Intron | chr2:141986752-142016944 | chr2:141229183-141259375 | 250 nt | 0.2880 |
| hsa_LRP1B_0039500 | Intron-Exon-Intron | chr2:141986752-142050227 | chr2:141229183-141292658 | 250 nt | 0.2800 |
| hsa_LRP1B_0039600 | Intron-Exon-Intron | chr2:141986752-142059438 | chr2:141229183-141301869 | 250 nt | 0.3200 |
| hsa_LRP1B_0039800 | Intron-Exon-Intron | chr2:141986752-142080047 | chr2:141229183-141322478 | 258 nt | 0.3101 |
Showing 411 to 420 of 509 entries
Forensic Context
A study in mice demonstrated that the circLRP1B is upregulated following traumatic brain injury, and its inhibition reduces inflammation and autophagy by regulating the miR-27a-3p/Dram2 signaling pathway [Li et al. DOI:10.1016/j.neuint.2023.105643].