Basic Information
Symbol
circLRP1B
RNA Class
circRNA
Alias
LDL Receptor Related Protein 1B
LRP-DIT
LRPDIT
Low Density Lipoprotein Receptor-Related Protein 1B
Low-Density Lipoprotein Receptor-Related Protein 1B
LRP-Deleted In Tumors
LRP-1B
Low Density Lipoprotein Receptor Related Protein-Deleted In Tumor
Low-Density Lipoprotein Receptor-Related Protein-Deleted In Tumor
Low Density Lipoprotein-Related Protein 1B (Deleted In Tumors)
EC 3.4.21.9
EC 1.1.1.94
Location (GRCh37)
2:140989360-142889270
UCSC Genome Browser
Location (GRCh38)
2:140231791-142131701
Host gene
LRP1B
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_LRP1B_0039700 | Intron-Exon-Intron | chr2:141986752-142178019 | chr2:141229183-141420450 | 250 nt | 0.3080 |
| hsa_LRP1B_0039900 | Exon-Exon | chr2:142004795-142012210 | chr2:141247226-141254641 | 126 nt | 0.3571 |
| hsa_LRP1B_0040000 | Intron-Intron | chr2:142079940-142093677 | chr2:141322371-141336108 | 250 nt | 0.3280 |
| hsa_LRP1B_0040100 | Intron-Exon-Intron | chr2:142079940-142238102 | chr2:141322371-141480533 | 138 nt | 0.4855 |
| hsa_LRP1B_0040200 | Intron-Intron | chr2:142081284-142081476 | chr2:141323715-141323907 | 193 nt | 0.4249 |
| hsa_LRP1B_0040300 | Intron-Intron | chr2:142081533-142081708 | chr2:141323964-141324139 | 176 nt | 0.4318 |
| hsa_LRP1B_0040400 | Intron-Intron | chr2:142101479-142101827 | chr2:141343910-141344258 | 349 nt | 0.4155 |
| hsa_chr2_0149800 | Intergenic-Intergenic | chr2:142113647-142113904 | chr2:141356078-141356335 | 258 nt | 0.3992 |
| hsa_LRP1B_0040500 | Intron-Exon-Intron | chr2:142134080-142238102 | chr2:141376511-141480533 | 250 nt | 0.3520 |
| hsa_LRP1B_0040600 | Intron-Intron | chr2:142134518-142134717 | chr2:141376949-141377148 | 200 nt | 0.3400 |
Showing 421 to 430 of 509 entries
Forensic Context
A study in mice demonstrated that the circLRP1B is upregulated following traumatic brain injury, and its inhibition reduces inflammation and autophagy by regulating the miR-27a-3p/Dram2 signaling pathway [Li et al. DOI:10.1016/j.neuint.2023.105643].